Subchronic Toxicity Study of 1,3-Propanediol Administered Orally to Rats
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چکیده
منابع مشابه
13-week subchronic toxicity study of a novel ginsenoside composition from ginseng leaves in rats
UG0712 is a new ginsenoside extract processed from ginseng leaves. A subchronic toxicity study of UG0712 was conducted in male and female SD rats. Rats were treated with UG0712 at doses of 100, 400 and 1,600 mg/kg/day for 13 weeks, and observed followed by 4-week recovery period at a highest dose. No-treatment-related effects were observed regarding the mortality, ophthalmic examination, urinal...
متن کاملSubchronic Inhalation Toxicity Study of n-pentane in Rats
OBJECTIVES This study was conducted in order to obtain information concerning the health hazards that may result from a 13 week inhalation exposure of n-pentane in Sprague-Dawley rats. METHODS This study was conducted in accordance with the Organization for Economic Co-operation and Development (OECD) guidelines for the testing of chemicals No. 413 'Subchronic inhalation toxicity: 90-day stud...
متن کاملThirteen-Week Study of PM014 Subchronic Oral Toxicity in Rats
PM014 is a modified herbal formula based on Chung-Sang-Bo-Ha-Tang, which is a well-known prescription drug used for curing various inflammatory pulmonary diseases. We previously showed that PM014 attenuated lung inflammation in a murine model of chronic obstructive pulmonary disease (COPD). The objective of the present study was to evaluate the chronic oral toxicity of PM014 in rats. PM014 was ...
متن کاملEvaluation of the Subchronic Toxicity of Dietary Administered Equisetum arvense in F344 Rats
Equisetum arvense, commonly known as the field horsetail, has potential as a new functional food ingredient. However, little information is available on its side effects, and the general toxicity of Equisetum arvense has yet to be examined in detail. In the present study, we evaluated the influence of administration in diet at doses of 0, 0.3, 1 and 3% for 13 weeks in male and female F344 rats....
متن کاملSubchronic toxicity study on soy isoflavones in rats.
OBJECTIVE To investigate the subchronic toxicity of soy isoflavones (SIF) in male rats. METHOD Fifty Sprague-Dawley rats were randomly divided into 5 groups, 10 rats per group. SIF were given to rats in different groups by gavage at dose of 0, 0.2, 0.5, 1.5, and 4.5 g/kg bw, respectively for 13 weeks. Clinical manifestations, body weight, and food consumption were observed weekly. At the end ...
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ژورنال
عنوان ژورنال: International Journal of Toxicology
سال: 2000
ISSN: 1091-5818,1092-874X
DOI: 10.1080/109158100225015